Formulation and Evaluation of Buccal Patches of Diclofenac Sodium

نویسنده

  • Shubhra Pandey
چکیده

Bilayerd films were prepared by solvent casting technique using different concentration of two polymers namely, sodium alginate and pectin. The backing membrane was prepared by using sodium alginate. The drug containing layer was prepared by using pectin. Different concentrations of plasticizers and permeation enhancers were added. Prepared films were evaluated for surface properties, weight variation, thickness, folding endurance, surface pH, drug content, swelling index and in vitro release. The release kinetics indicated first order release of drug from all formulation.

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تاریخ انتشار 2012